Osteoporosis and phosphate?
what would happen if someone consumes a lot of phosphate while having hypocalcemia (which lead this person to osteoporosis)? would they be kiney stones? what else?
Answers:
Excretion of phosphate and calcium share an inverse relationship, so if they were already hypocalcemic, it is possible that they could lose even more calcium -- so, yes it would exacerbate any existing osteoporosis. Most renal stones are calcium stones, and supersaturation of the renal system is the primary predisposing influence -- thus, a hypocalcemic patient would not be at any greater risk for developing renal stones because their calcium levels would likely be insufficient to supersaturate the renal system.
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